Fa'amatalaga Oloa

Faailoga o oloa

Quickmice™ Fast KI Mouse Customization

quickmice-fast-ki-mouse-customization-product

Tu'itu'i (Knock-in, KI) ose metotia e fa'aogaina ai le toe tu'ufa'atasiga tutusa o kenera e fa'afeiloa'i ai se ga'o galue i fafo i se fa'asologa tutusa i totonu o le sela ma le genome, ma maua ai fa'amatalaga lelei i totonu o le sela pe a mae'a le toe tu'ufa'atasiga.

E manaʻomia le 5-6 masina e maua ai neo-deleted heterozygous mice ma le aofaʻi o 10-12 masina e fausia ai se KI homozygous faʻataʻitaʻiga isumu ma maualalo fua faʻatatau e faʻaaoga ai auala masani, aua o nei metotia e maualalo le chimera positivity ma manaʻomia le faʻaipoipo ma se isumu e. maua neo-deleted heterozygous isumu, ona fa'atupuina lea o isumu heterozygous fanau mai mo le 2-3 augatupulaga e maua ai le homozygous KI isumu.

Ose augatupulaga fou o Fa'atekonolosi Sauniuniga Iole

TurboMice™

E mafai ona matou vave tuʻuina atu ia te oe faʻataʻitaʻiga KI homozygous mouse e ala i le faʻaogaina o tekinolosi TurboMice ™ e faʻaleleia ai le tulaga manuia.

Fa'avae i luga o le polokalame fa'ata'ita'iga sili ona lelei a tatou saienitisi, e mafai ona fa'amae'aina le su'esu'eina o sela fa'ato'a fa'ata'oto i totonu ole 3-5 aso, ona fausia lea o le embryo tetraploid.A maeʻa le faʻataʻitaʻiina o tina, e mafai ona maua maisu homozygous humanized i totonu ole 2-4 masina, lea e mafai ona faʻapolopolo 7-8 masina mo tagata faʻatau.

Auaunaga i totonu

Auaunaga Nu. Fa'ailoga fa'apitoa Tiliva mea Taamilosaga tiliva
MC002-1 umi ole gene tasi <5kb 3-9 KI isumu tane homozygous 2-4 masina
MC002-2 umi ole gene tasi <5kb 10-19 KI isumu tane homozygous 2-4 masina
MC002-3 umi ole gene tasi <5kb 20 KI isumu tane homozygous 3-5 masina
MC002-4 umi ole gene tasi e 5kb-10kb 3-9 KI isumu tane homozygous 3-4 masina
MC002-5 umi ole gene tasi e 5kb-10kb 10-19 KI isumu tane homozygous 3-4 masina
MC002-6 umi ole gene tasi e 5kb-10kb 20 KI isumu tane homozygous 3-5 masina

Faafesootai matou

Fa'amolemole fa'afeso'ota'i ma matou ile:

1) Fa'amolemole download ma fa'atumu le fomu i lalo《Pepa talosaga mo upusii》, ma lafo mai ile imeli ileMingCelerOversea@mingceler.com;

2) Te: +86 181 3873 9432;

3) LinkedIn: https://www.linkedin.com/company/mingceler/

Pepa talosaga mo upusii.docx

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